Symmetrical drug-related intertriginous and flexural exanthema induced by dual beta-lactam antibiotics

Abstract: This report highlights a rare case where an 88-year-old woman developed symmetrical drug-related intertriginous and flexural exanthema, induced by concomitant treatment with intravenous injections of two beta-lactam antibiotics, namely ceftriaxone and piperacillin–tazobactam. This case emphasizes the importance of minimizing dual beta-lactam usage and on the need for early detection and management of this rare adverse drug reaction.