Lipidomics changes in bronchoalveolar lavage fluid of refractory mycoplasma pneumoniae pneumonia: LC-MS-based analysis of potential biomarkers and pathogenesis
This is the first study to analyze the lipidomic features of BALF to differentiate between RMPP and MPP. The lipidomics of BALF in patients with RMPP was significantly altered and closely correlated with clinically relevant indicators. These data may contribute to the understanding of the pathogenesis of RMPP and the discovery of new biomarkers and therapeutic targets for RMPP.
Authors
- Howard J. Huang (ORCID: https://orcid.org/0000-0002-3358-6795)
- Jiao Shi (ORCID: https://orcid.org/0000-0002-5295-8961)
- Weigang Wang (ORCID: https://orcid.org/0000-0002-1130-0143)
- Xiaofei Li (ORCID: https://orcid.org/0000-0003-3727-0066)
- Miao Ma (ORCID: https://orcid.org/0000-0002-9612-7940)
Institutions
- Northwest Women's and Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3389/fped.2025.1655289
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00