The Association Between the Triglyceride–Glucose Index and the Risk of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study

The TGI was shown to be associated with a significantly higher risk of a MACE, CAD, CHF, and MI in the whole population, along with stroke in males only. The TGI was more strongly associated with MACEs in patients younger than 60 years compared to older patients. In conclusion, the TGI was associated with cardiovascular outcomes in this diabetic cohort; however, its discriminative ability was modest (AUC 0.55-0.64). This indicates that the TGI alone is insufficient as a predictive tool and should be interpreted alongside established risk factors. Prospective studies are needed to clarify its incremental value in risk prediction.