Snapshot Genomic Surveillance Reveals Insights into Antimicrobial Resistance and Lineage Diversity of Uropathogens in Older Adults in Queensland
Community-acquired UTIs in older adults are predominantly caused by diverse <i>E. coli</i> lineages, with limited evidence of transmission within aged care facilities. The low rates of AMR in the community, along with the absence of strains adapted to a particular setting, suggest that current empiric therapy guidelines remain appropriate. Our prospective genomic surveillance offers valuable insights for monitoring UTIs in this population. It demonstrates the importance of an unbiased approach to accurately capture the prevalence and diversity of uropathogen lineages.
Authors
- Johanna Mayer‐Coverdale
- Caitlin Falconer (ORCID: https://orcid.org/0000-0002-0476-7714)
- David L. Paterson (ORCID: https://orcid.org/0000-0003-2079-4437)
- Brian M. Forde (ORCID: https://orcid.org/0000-0002-2264-4785)
- Thom Cuddihy (ORCID: https://orcid.org/0000-0003-3071-7742)
- Patrick N. A. Harris (ORCID: https://orcid.org/0000-0002-2895-0345)
- Mark A. Schembri (ORCID: https://orcid.org/0000-0003-4863-9260)
- Jennifer Robson (ORCID: https://orcid.org/0000-0001-7207-244X)
- Budi Permana (ORCID: https://orcid.org/0009-0000-7448-7235)
Institutions
- Queensland Health (AU)
- The University of Queensland (AU)
- National University of Singapore (SG)
- Royal Brisbane and Women's Hospital (AU)
- Metro South Health (AU)
- National University Health System (SG)
- Sullivan Nicolaides Pathology (AU)
- Central Queensland University (AU)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1093/ofid/ofaf610
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00