Patients with langerhans cell histiocytosis and hypothalamic-pituitary involvement: insights from the HEROS study cohort

Patients with LCH and hypothalamic-pituitary involvement remained clinically stable during long-term follow-up. However, new hormonal deficits may develop years after diagnosis, with most patients ultimately experiencing AVD.

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Publication Details

Journal
Pituitary
Published
2025-09-26
DOI
https://doi.org/10.1007/s11102-025-01576-3
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Patients with langerhans cell histiocytosis and hypothalamic-pituitary involvement: insights from the HEROS study cohort

Miklós Tóth, Hiba Masri Iraqi, Yona Greenman, Gregory Kaltsas et al.
Pituitary
Histiocytic Disorders and Treatments
article

Patients with langerhans cell histiocytosis and hypothalamic-pituitary involvement: insights from the HEROS study cohort

Miklós Tóth, Hiba Masri Iraqi, Yona Greenman, Gregory Kaltsas, Ekaterina Pigarova, Diego Ferone, Lior Baraf, Marina Tsoli, Amit Akirov, Ilan Shimon, Annamaria Colao, Mirjana Doknić
article en

Abstract

Patients with LCH and hypothalamic-pituitary involvement remained clinically stable during long-term follow-up. However, new hormonal deficits may develop years after diagnosis, with most patients ultimately experiencing AVD.

PituitaryVol. 28(5)
Semmelweis University (HU), University of Padua (IT), Tel Aviv University (IL), Tel Aviv Sourasky Medical Center (IL), Rabin Medical Center (IL), Soroka Medical Center (IL), University of Belgrade (RS), Endocrinology Research Center (RU), Laiko General Hospital of Athens (GR), Ospedale Policlinico San Martino (IT), University of Naples Federico II (IT)
Openalex Percentile: Top 67%
Histiocytic Disorders and Treatments
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