Clinical presentation, predictive factors and management of patients with Nelson syndrome: a retrospective study
CTP-BADX/NS occurred in 30% of cases in our cohort. Higher ACTH post-BADX and younger age at CD onset may predict NS. No hormonal or radiological markers reliably predicted tumor progression. SRS before BADX and higher hydrocortisone doses might offer protection. Tumor control often needed a multimodal approach, with limited success from medical therapy alone.
Authors
- Mattia Barbot (ORCID: https://orcid.org/0000-0002-1081-5727)
- Luca Denaro (ORCID: https://orcid.org/0000-0002-2529-6149)
- Alessandro Mondin (ORCID: https://orcid.org/0000-0002-6046-5198)
- Filippo Ceccato (ORCID: https://orcid.org/0000-0003-1456-8716)
- Mario Caccese (ORCID: https://orcid.org/0000-0002-0059-5660)
- Pierluigi Mazzeo
- Renzo Manara (ORCID: https://orcid.org/0000-0002-5130-3971)
- Giacomo Voltan (ORCID: https://orcid.org/0000-0002-3628-0492)
- Giulia Bovo
Institutions
- University of Padua (IT)
- Istituto Oncologico Veneto (IT)
Publication Details
- Journal
- Pituitary
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1007/s11102-025-01579-0
- Citations
- 1
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.29