Bone scan revelation: rib lesion diagnosed as diffuse large B cell lymphoma

Diffuse Large B-Cell Lymphoma (DLBCL), a highly aggressive tumour, is the most prevalent form of non-Hodgkin lymphoma (NHL), staged with 18F-flourodeoxyglucose positron emission tomography/computed tomography (18F FDG PET/CT) although conventional radiological imaging may be employed occasionally. DLBCL may present in an atypical manner, resulting in detection by alternate imaging modalities such a bone scan, which is usually not the first choice in the workup. We present an interesting case where a solitary osseous lesion was initially detected by bone scan with single photon emission computed tomography (SPECT-CT) leading to timely diagnosis and management of the patient.