Myeloid sarcoma with acute myeloid leukaemia: a case report of rare presentation

Myeloid sarcoma (MS) is a rare extramedullary manifestation of acute myeloblastic leukaemia (AML). The presentation of MS depends on the anatomical location being affected. Myeloid sarcoma can also occur in the absence of AML, but when they occur simultaneously, they are often associated with a poorer prognosis. We report the case of an adolescent patient of AML with MS of cervical lymph nodes presenting with vague and non specific complaint of abdominal pain for two months with history of a non-specific and non-healing skin lesion on the right lower extremity. Detailed history and physical examination were a major help. Bone marrow biopsy and cervical lymph node biopsy were performed to make the definitive diagnosis. Chemotherapy and supportive care were administered. Since such cases are rarely encountered, they tend to be misdiagnosed. Reporting cases with such variable presentations can help physicians not to miss such important differential diagnoses in their evaluation.

Authors

Institutions

Publication Details

Journal
Journal of the Pakistan Medical Association
Published
2025-09-25
DOI
https://doi.org/10.47391/jpma.22211
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Myeloid sarcoma with acute myeloid leukaemia: a case report of rare presentation

Harris Siddiqi, Ammara Saleem, Kausar Bano, A M John et al.
Journal of the Pakistan Medical Association
Acute Myeloid Leukemia Research
article

Myeloid sarcoma with acute myeloid leukaemia: a case report of rare presentation

Harris Siddiqi, Ammara Saleem, Kausar Bano, A M John, Amjad Zafar
article en

Abstract

Myeloid sarcoma (MS) is a rare extramedullary manifestation of acute myeloblastic leukaemia (AML). The presentation of MS depends on the anatomical location being affected. Myeloid sarcoma can also occur in the absence of AML, but when they occur simultaneously, they are often associated with a poorer prognosis. We report the case of an adolescent patient of AML with MS of cervical lymph nodes presenting with vague and non specific complaint of abdominal pain for two months with history of a non-specific and non-healing skin lesion on the right lower extremity. Detailed history and physical examination were a major help. Bone marrow biopsy and cervical lymph node biopsy were performed to make the definitive diagnosis. Chemotherapy and supportive care were administered. Since such cases are rarely encountered, they tend to be misdiagnosed. Reporting cases with such variable presentations can help physicians not to miss such important differential diagnoses in their evaluation.

Journal of the Pakistan Medical AssociationVol. 75(10)
Jinnah Postgraduate Medical Center (PK), Allama Iqbal Medical College (PK), Shaukat Khanum Memorial Cancer Hospital and Research Center (PK)
Openalex Percentile: Top 66%
Acute Myeloid Leukemia Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.