Hyperactive Enteric Glia Contribute to Persistent Dysmotility Following Inflammation by Driving Aberrant Excitatory Responses in Neurons
These observations suggest that therapies targeting enteric glial signaling mechanisms could aid persistent gut dysmotility caused by inflammation.
Authors
- Visha Parmar (ORCID: https://orcid.org/0000-0001-8826-7452)
- Brian D. Gulbransen (ORCID: https://orcid.org/0000-0003-1145-3227)
- Silvia Basili Franzin (ORCID: https://orcid.org/0000-0001-7114-9089)
- Jonathon L. McClain
- Luisa Seguella (ORCID: https://orcid.org/0000-0003-2346-9912)
- Giuseppe Esposito (ORCID: https://orcid.org/0000-0001-8080-8218)
- Beatriz Thomasi (ORCID: https://orcid.org/0000-0002-9322-7567)
- Aurora Zilli (ORCID: https://orcid.org/0009-0001-8986-8011)
- Rafaella Lavalle
Institutions
- Sapienza University of Rome (IT)
- Michigan State University (US)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.jcmgh.2025.101634
- Citations
- 2
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.62