Association of TLR2 (rs5743708) Gene Polymorphism with Asthma Susceptibility and the Impact of Smoking: (Case-Control Study).
This suggests a gene-environment interaction involving the TLR2 polymorphism and smoking, indicating an elevated risk and severity of asthma. The study's results underscore the importance of genetic assessment in chronic asthma patients, particularly in the context of smoking exposure, to inform treatment and management strategies.
Authors
- Eman Mostafa Nassef (ORCID: https://orcid.org/0000-0002-3109-6143)
- Ahmed Kabil (ORCID: https://orcid.org/0000-0003-1910-9674)
- Mohamed Abdelrahman (ORCID: https://orcid.org/0000-0001-5798-9671)
- Mohammad AbdElhameed Alwaseef
- Moustafa M Rabie (ORCID: https://orcid.org/0000-0002-9988-4592)
- Mahmoud Mohammed Mohammed Metwally
- Mona Mohamed Abdulwehab
- Asmaa Ali (ORCID: https://orcid.org/0000-0001-6816-2821)
- Mohamed Khedr (ORCID: https://orcid.org/0000-0001-6118-8607)
- Hatem Mohamed Newishy
- Nagah M. Abu-Mohammed
- Sherein M. Alnabawy
- Mohamed Farouk Ibrahim Mosa
- Hesham Hegazy
- Amira M. Negm (ORCID: https://orcid.org/0009-0000-7293-3430)
- Omima Sayed Mohammed
- Abdulmabod Omar
- Zeinab Adawy
- Eid Mohammed
- M. Rizk
- Nora El Saeed Abdelbaset
- Badawy W Abo-Bakr
- Omnia Shams Gouda
- Mahmoud Ahmed Arfa
Institutions
- Al-Azhar University (EG)
- King Abdulaziz University (SA)
- Tanta University (EG)
Publication Details
- Journal
- PubMed
- Published
- 2025-09-25
- DOI
- https://doi.org/10.7417/ct.2025.5275
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00