Value of the diagnostic algorithm in differentiating glioblastoma from solitary brain metastasis and primary central nervous system lymphomas using Dynamic susceptibility contrast-enhanced MRI (DSCE-MRI) and Proton magnetic resonance spectroscopy (1H

The values obtained from DSCE, 1H-MRS, and the diagnostic model play a crucial role in differentiating GBM, SM, and solitary PCNSLs. Our DSCE and 1H-MRS-based algorithm accurately differentiates GBM, SM, and PCNSLs, achieving 100% sensitivity and 98.9% specificity. This non-invasive method enhances pre-treatment diagnosis and prognosis, improving diagnostic quality for patients.