Click Synthesis and Spectral Characterization of a 1,2,3-Triazole Conjugated Pyrrole-2,5-dione Scaffold
This study presents the synthesis and characterization of a novel 1,2,3-triazole conjugated pyrrole-2,5-dione compound via copper-catalyzed azide-alkyne cycloaddition (click chemistry). The synthetic route involves the reaction of benzyl azide with a pyrrole-2,5-dione-derived alkyne under mild conditions, yielding the target compound in excellent purity and yield (92 percent). The final product was comprehensively characterized using FT-IR, <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, and high-resolution mass spectrometry, confirming its structural integrity. The reported methodology contributes to the development of bioactive heterocyclic scaffolds with potential pharmaceutical relevance.
Authors
- Ram Kumar (ORCID: https://orcid.org/0000-0001-7248-4217)
- V. Anil Kumar (ORCID: https://orcid.org/0000-0001-5391-754X)
- Nitesh Kumar (ORCID: https://orcid.org/0000-0002-1584-8907)
- Saba Khan
- Urvashi Mishra
Publication Details
- Journal
- International Journal of Science and Research (IJSR)
- Published
- 2025-09-26
- DOI
- https://doi.org/10.21275/sr25923100202
- Primary Topic
- Synthesis and Characterization of Pyrroles
- Type
- article
- Field-Weighted Citation Impact
- 0.00