Diagnostic and prognostic significance of Super-enhancer-associated genes in Crohn’s disease and immune regulatory roles
PAQR5, IFITM3, PSMB8, and IRF1 serve as biomarkers for CD, offering substantial diagnostic and immune regulatory value. These biomarkers differentiate CD into two subtypes, providing insights for personalized therapeutic strategies.
Authors
- Xiaoyun Wu
- Yan Ming Fang (ORCID: https://orcid.org/0000-0002-7351-0816)
- Yuanyuan Li (ORCID: https://orcid.org/0000-0003-4967-3890)
- Yang Yang (ORCID: https://orcid.org/0000-0002-6306-1324)
Institutions
- Chengdu Fifth People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s40001-025-03168-0
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00