Blast Overpressure-Induced Neuroinflammation and Axonal Injury in the Spinal Cord of Ferrets
Our results indicate that blast exposure causes acute and sub-acute neuroinflammation and associated axonal injury in the cervical spinal cord. These data further suggest that inhibition of <i>TLR</i>s and/or <i>COX-2</i> enzyme might offer protection against blast-induced injuries to the spinal cord.
Authors
- Peethambaran Arun (ORCID: https://orcid.org/0000-0002-0975-412X)
- Ali Al-lami (ORCID: https://orcid.org/0000-0002-2140-7681)
- Manoj Govindarajulu (ORCID: https://orcid.org/0000-0003-4739-648X)
- Chetan Pundkar (ORCID: https://orcid.org/0000-0001-8864-8546)
- Rex Jeya Rajkumar Samdavid Thanapaul (ORCID: https://orcid.org/0000-0002-5760-9437)
- Anil Menon (ORCID: https://orcid.org/0000-0002-6886-3553)
- Joseph B. Long
- Gaurav Phuyal
Institutions
- University of Maryland, Baltimore County (US)
- Walter Reed Army Institute of Research (US)
Publication Details
- Journal
- Brain Sciences
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3390/brainsci15101050
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00