Identification of urinary bacterial genes as biomarkers for non-invasive diagnosis of renal lupus

Some bacterial genes have been identified in the urobiome of SLE patients that allow differentiation between those with renal and non-renal lupus. These findings offer valuable insight into the association between the urobiome and SLE presentation, and lay the foundation for developing novel diagnostic tools that overcome the limitations of current methods, thereby improving patient care.

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Publication Details

Journal
Biomarker Research
Published
2025-09-26
DOI
https://doi.org/10.1186/s40364-025-00828-5
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
0.00

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Identification of urinary bacterial genes as biomarkers for non-invasive diagnosis of renal lupus

Virginia Pérez‐Carrasco, Torsten Witte, Ángel Linde-Rodríguez, Bernard Lauwerys et al.
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Identification of urinary bacterial genes as biomarkers for non-invasive diagnosis of renal lupus

Virginia Pérez‐Carrasco, Torsten Witte, Ángel Linde-Rodríguez, Bernard Lauwerys, Michaela Lehner, Enrique Raya, Anne‐Lise Maudoux, Antonio López‐Berrio, Gabriella Kádár, Georg Stummvoll, Falk Hiepe, José A. García‐Salcedo, Attila Balog, Miguel Ángel González-Gay, N. Ortego, Velia Gerl, Rik Lories, Carlos Vasconcelos, Ana Campar, José Gutiérrez Fernández, Concepción Marañón, Pier Luigi Meroni, Matilde Ortiz-González, Alain Saraux, Esmeralda Neves, Victoria Sánchez-Martín, Sonja Dulic, Mariana Brandão, Ricard Cervera, Tânia Gomes Anjos, Donatienne Wynar, Maria Luisa García‐Martín, Michael Zauner, Yiannis Ioannou, Gerard Espinosa, Aleksandra Zuber, Nicolas Hunzelmann, Rocío Aguilar‐Quesada, Tommaso Schioppo, R. Ortega Castro, Cinzia Guzzi, Valérie Devauchelle‐Pensec, Eduardo Collantes‐Estévez, Marta E. Alarcón‐Riquelme, António Marinho, Isabel Díaz Quintero, Barbara Vigone, Márta Bocskai, Ignasi Rodríguez‐Pintó, Magdolna Deák, María Concepción Fernández Roldán, Niklas Baerlecken, Ana Soriano‐Lerma, Héctor Navarro‐Linares, Carolina Artusi, Fátima Farinha, M. Á. Aguirre, Raquel Faria, Yolanda Jiménez, Maria Gerosa, Carlo Chizzolini, Isabel Almeida, Jacqueline Marovac, Lorenzo Beretta, Ricardo Blanco, Jacques‐Olivier Pers, Manuel Rodríguez Maresca, Miguel Soriano, László Kovács, Julie Ducreux, M. Tello, Ellen De Langhe, Silvia Thiel, Doreen Belz, Divi Cornec, Ana Tavares, Alfonso Corrales Martínez, Alejandro Escudero-Contreras, Inmaculada Jiménez Moleón, Marta Alarcón Riquelme, Chris Chamberlain, Enrique de Ramón, Sandrine Jousse-Joulin, Ma Carmen Castro‐Villegas
article en

Abstract

Some bacterial genes have been identified in the urobiome of SLE patients that allow differentiation between those with renal and non-renal lupus. These findings offer valuable insight into the association between the urobiome and SLE presentation, and lay the foundation for developing novel diagnostic tools that overcome the limitations of current methods, thereby improving patient care.

Biomarker ResearchVol. 13(1)
Universidad de Granada (ES), Fundación Progreso y Salud (ES), Instituto de Investigación Biosanitaria de Granada (ES), Hospital Universitario Virgen de las Nieves (ES), Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research (ES), Andalusian Centre for Nanomedicine and Biotechnology (ES), Instituto de Investigación Biomédica de Málaga (ES), University of Almería (ES)
Junta de Andalucía, European Regional Development Fund
Openalex Percentile: Top 61%
Systemic Lupus Erythematosus Research
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