Identification of urinary bacterial genes as biomarkers for non-invasive diagnosis of renal lupus
Some bacterial genes have been identified in the urobiome of SLE patients that allow differentiation between those with renal and non-renal lupus. These findings offer valuable insight into the association between the urobiome and SLE presentation, and lay the foundation for developing novel diagnostic tools that overcome the limitations of current methods, thereby improving patient care.
Authors
- Virginia Pérez‐Carrasco (ORCID: https://orcid.org/0000-0003-4233-8969)
- Torsten Witte
- Ángel Linde-Rodríguez (ORCID: https://orcid.org/0000-0001-5954-8562)
- Bernard Lauwerys (ORCID: https://orcid.org/0000-0003-3243-6151)
- Michaela Lehner
- Enrique Raya (ORCID: https://orcid.org/0000-0002-2184-6182)
- Anne‐Lise Maudoux
- Antonio López‐Berrio
- Gabriella Kádár
- Georg Stummvoll
- Falk Hiepe (ORCID: https://orcid.org/0000-0003-3584-5292)
- José A. García‐Salcedo (ORCID: https://orcid.org/0000-0003-3399-1835)
- Attila Balog (ORCID: https://orcid.org/0000-0003-0899-4655)
- Miguel Ángel González-Gay (ORCID: https://orcid.org/0000-0002-7924-7406)
- N. Ortego
- Velia Gerl
- Rik Lories (ORCID: https://orcid.org/0000-0002-5986-3092)
- Carlos Vasconcelos (ORCID: https://orcid.org/0000-0002-8073-5028)
- Ana Campar (ORCID: https://orcid.org/0000-0002-3951-8961)
- José Gutiérrez Fernández (ORCID: https://orcid.org/0000-0001-6146-9740)
- Concepción Marañón (ORCID: https://orcid.org/0000-0002-7827-6301)
- Pier Luigi Meroni (ORCID: https://orcid.org/0000-0002-3394-1451)
- Matilde Ortiz-González (ORCID: https://orcid.org/0000-0001-9977-5735)
- Alain Saraux (ORCID: https://orcid.org/0000-0002-8454-7067)
- Esmeralda Neves (ORCID: https://orcid.org/0000-0002-7754-8109)
- Victoria Sánchez-Martín (ORCID: https://orcid.org/0000-0001-6870-3659)
- Sonja Dulic
- Mariana Brandão (ORCID: https://orcid.org/0000-0003-2016-6932)
- Ricard Cervera (ORCID: https://orcid.org/0000-0001-6085-492X)
- Tânia Gomes Anjos (ORCID: https://orcid.org/0000-0002-9596-1626)
- Donatienne Wynar
- Maria Luisa García‐Martín (ORCID: https://orcid.org/0000-0002-2257-7682)
- Michael Zauner
- Yiannis Ioannou
- Gerard Espinosa (ORCID: https://orcid.org/0000-0003-1336-0163)
- Aleksandra Zuber
- Nicolas Hunzelmann
- Rocío Aguilar‐Quesada (ORCID: https://orcid.org/0000-0003-3125-6634)
- Tommaso Schioppo (ORCID: https://orcid.org/0000-0001-8359-5131)
- R. Ortega Castro (ORCID: https://orcid.org/0000-0002-7552-3469)
- Cinzia Guzzi (ORCID: https://orcid.org/0000-0002-1035-4959)
- Valérie Devauchelle‐Pensec (ORCID: https://orcid.org/0000-0003-0432-825X)
- Eduardo Collantes‐Estévez (ORCID: https://orcid.org/0000-0002-7647-6289)
- Marta E. Alarcón‐Riquelme (ORCID: https://orcid.org/0000-0002-7632-4154)
- António Marinho (ORCID: https://orcid.org/0000-0002-3295-6723)
- Isabel Díaz Quintero
- Barbara Vigone
- Márta Bocskai
- Ignasi Rodríguez‐Pintó (ORCID: https://orcid.org/0000-0001-6193-6396)
- Magdolna Deák
- María Concepción Fernández Roldán
- Niklas Baerlecken
- Ana Soriano‐Lerma (ORCID: https://orcid.org/0000-0003-2830-1457)
- Héctor Navarro‐Linares
- Carolina Artusi
- Fátima Farinha (ORCID: https://orcid.org/0000-0003-0215-0806)
- M. Á. Aguirre (ORCID: https://orcid.org/0000-0002-5653-4293)
- Raquel Faria (ORCID: https://orcid.org/0000-0002-2956-1966)
- Yolanda Jiménez (ORCID: https://orcid.org/0000-0002-1607-2717)
- Maria Gerosa (ORCID: https://orcid.org/0000-0001-5241-5847)
- Carlo Chizzolini (ORCID: https://orcid.org/0000-0003-4849-6335)
- Isabel Almeida (ORCID: https://orcid.org/0000-0002-8867-1540)
- Jacqueline Marovac
- Lorenzo Beretta (ORCID: https://orcid.org/0000-0002-6529-6258)
- Ricardo Blanco (ORCID: https://orcid.org/0000-0003-2344-2285)
- Jacques‐Olivier Pers (ORCID: https://orcid.org/0000-0001-7287-5541)
- Manuel Rodríguez Maresca
- Miguel Soriano (ORCID: https://orcid.org/0000-0002-1838-3615)
- László Kovács (ORCID: https://orcid.org/0000-0002-7337-5626)
- Julie Ducreux
- M. Tello
- Ellen De Langhe
- Silvia Thiel
- Doreen Belz
- Divi Cornec
- Ana Tavares
- Alfonso Corrales Martínez
- Alejandro Escudero-Contreras
- Inmaculada Jiménez Moleón
- Marta Alarcón Riquelme
- Chris Chamberlain
- Enrique de Ramón
- Sandrine Jousse-Joulin
- Ma Carmen Castro‐Villegas
Institutions
- Universidad de Granada (ES)
- Fundación Progreso y Salud (ES)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Hospital Universitario Virgen de las Nieves (ES)
- Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research (ES)
- Andalusian Centre for Nanomedicine and Biotechnology (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
- University of Almería (ES)
Publication Details
- Journal
- Biomarker Research
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s40364-025-00828-5
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Junta de Andalucía
- European Regional Development Fund