Thyroid Nodules with Indeterminate Cytological Category in Pediatric Age: Clinical and Surgical Management and Outcome in an Italian Multicentre Retrospective Study

The reported data seem to confirm a greater sensitivity of SIAPEC classification to identify malignancy within the indeterminate category also in pediatric age and not only in adulthood. This finding may orient clinicians toward clinical follow-up for the indeterminate TIR3a group and toward surgical approach with total thyroidectomy in the indeterminate TIR3b group, although this indication should be confirmed in further national multicenter studies including larger cohorts.

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Publication Details

Journal
Hormone Research in Paediatrics
Published
2025-09-25
DOI
https://doi.org/10.1159/000548521
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Thyroid Nodules with Indeterminate Cytological Category in Pediatric Age: Clinical and Surgical Management and Outcome in an Italian Multicentre Retrospective Study

Małgorzata Waśniewska, Francesco Quaglino, Luisa De Sanctis, Giorgia Pepe et al.
Hormone Research in Paediatrics
Thyroid Cancer Diagnosis and Treatment
article

Thyroid Nodules with Indeterminate Cytological Category in Pediatric Age: Clinical and Surgical Management and Outcome in an Italian Multicentre Retrospective Study

Małgorzata Waśniewska, Francesco Quaglino, Luisa De Sanctis, Giorgia Pepe, Gerdi Tuli, Jessica Munarin, Francesca Franchina, Maria Cristina Vigone, Tommaso Aversa, Marco Abbate
article en

Abstract

The reported data seem to confirm a greater sensitivity of SIAPEC classification to identify malignancy within the indeterminate category also in pediatric age and not only in adulthood. This finding may orient clinicians toward clinical follow-up for the indeterminate TIR3a group and toward surgical approach with total thyroidectomy in the indeterminate TIR3b group, although this indication should be confirmed in further national multicenter studies including larger cohorts.

Hormone Research in Paediatrics
University of Messina (IT), Vita-Salute San Raffaele University (IT), Martin University (US), Ospedale Regina Margherita (IT), Ospedale Maria Vittoria (IT), University of Turin (IT)
Openalex Percentile: Top 64%
Thyroid Cancer Diagnosis and Treatment
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