Adiponectin pathway regulates cerebral metabolic dysfunction and neuroinflammation via the AdipoR1/PI3K/Akt axis in Perioperative Neurocognitive Disorder
The adiponectin pathway regulates cerebral metabolic dysfunction and neuroinflammation via the AdipoR1/PI3K/Akt axis, which serves as a potential therapeutic target for improving perioperative cognitive outcomes in elderly patients.
Authors
- Chonghui Hu
- Chengzhi Zhong (ORCID: https://orcid.org/0000-0003-1741-7219)
- Baiqin Su
- Zhijing Zhang (ORCID: https://orcid.org/0000-0002-3769-569X)
- Lideng Guo
- Binbin Li (ORCID: https://orcid.org/0000-0002-8572-8003)
- Huiqun Chen (ORCID: https://orcid.org/0000-0002-0993-1480)
- Haihui Xie
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- North China University of Science and Technology Affiliated Hospital (CN)
- Dongguan People’s Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s12877-025-06367-w
- Citations
- 1
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- Guangdong Medical Research Foundation
- Basic and Applied Basic Research Foundation of Guangdong Province