Malignant Mucosal Melanoma of the Paranasal Sinuses
Sinonasal melanoma is a rare malignant tumor arising from the melanocytes of the paranasal sinuses. It has local and distant metastasis. This study reports a case of sinonasal melanoma at King Abdullah Medical Center. A 74-year-old male patient presented with unilateral nasal obstruction and epistaxis. A contrast-enhanced CT scan of the brain and paranasal sinuses showed findings suggestive of invasive fungal sinusitis. Following this finding, the patient was referred for an MRI scan, which confirmed the aggressive nature of the mass. Subsequently, a biopsy was taken from the mass, which proved sinonasal melanoma. The patient underwent surgical resection of the lesion. Histopathology confirmed the diagnosis of sinonasal melanoma. Unfortunately, the patient passed away one week after the operation.
Authors
- Afsheen Mahboob
- Naglaa Mostafa Elsayed
- Aisha Almassawi
Institutions
- Cairo University (EG)
- King Abdulaziz University (SA)
- King Abdullah International Medical Research Center (SA)
- King Abdullah Medical City (SA)
Publication Details
- Journal
- Cureus
- Published
- 2025-09-26
- DOI
- https://doi.org/10.7759/cureus.93257
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00