A novel phex gene variant causes non-syndromic tooth agenesis
Our research not only advances the understanding of NSTA pathogenic mechanisms but also expands the phenotypic spectrum associated with PHEX variants, highlighting its role beyond phosphate homeostasis in the development of specific dental structures.
Authors
- Yuhua Pan (ORCID: https://orcid.org/0000-0001-8039-1627)
- Baolai Hua (ORCID: https://orcid.org/0000-0002-1712-0768)
- Shenglong Tan (ORCID: https://orcid.org/0000-0002-6599-7230)
- Dandan Ma (ORCID: https://orcid.org/0000-0003-4484-9455)
- Fu Xiong (ORCID: https://orcid.org/0000-0002-8748-4890)
- He Wang (ORCID: https://orcid.org/0000-0001-9736-8028)
- Ting Lu (ORCID: https://orcid.org/0000-0002-6040-3210)
Institutions
- Guangdong Province Stomatological Hospital (CN)
- Key Laboratory of Guangdong Province (CN)
- Nanfang Hospital (CN)
- Cell Technology (China) (HK)
- Zhujiang Hospital (CN)
- Stomatology Hospital (CN)
- Southern Medical University (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s12903-025-06827-0
- Primary Topic
- dental development and anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Southern Medical University
- Basic and Applied Basic Research Foundation of Guangdong Province