Disulfidptosis OXSM serves as a potential prognostic biomarker and correlates with immune infiltrates in glioma
Our study identifies OXSM as a key DRG hub gene in glioma, with elevated expression strongly correlating with poor patient prognosis. The observed relationship between OXSM expression and immune cell infiltration suggests its potential role in modulating the glioma microenvironment. These findings advance our understanding of glioma's molecular mechanisms and may inform the development of novel therapeutic strategies.
Authors
- Shengdong Nie (ORCID: https://orcid.org/0000-0001-7825-4455)
- Jinchao Zhu (ORCID: https://orcid.org/0000-0003-2821-4847)
- Qingyuan Lin
- Yijuan Fan
- Ke Yao (ORCID: https://orcid.org/0000-0002-0245-6445)
- Wenhuan Guo
- Weiyao Zhu
Institutions
- University of Shanghai for Science and Technology (CN)
- Renji Hospital (CN)
- Shanghai Ninth People's Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1007/s12672-025-03491-2
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Natural Science Foundation of Shanghai
- National Natural Science Foundation of China
- Shanghai Key Laboratory of Molecular Imaging