Molecular epidemiology and increasing macrolide resistance of Bordetella pertussis isolates in Guangzhou, China
Our findings demonstrate the current dominance of macrolide-resistant B. pertussis strain harboring ptxP3 and prn150 in Guangzhou since 2024. This study provides epidemiological and microbiological insights to guide local pertussis control strategies and to offer antimicrobial resistance monitoring efforts.
Authors
- Chunming Gu
- Dongping Huang (ORCID: https://orcid.org/0000-0003-3931-8385)
- Zhenhui Chen (ORCID: https://orcid.org/0000-0001-7680-533X)
- Mingyong Luo (ORCID: https://orcid.org/0000-0002-1202-1429)
- Cunwei Ji
- Hengguang Li (ORCID: https://orcid.org/0000-0001-9283-7366)
- Minling Zheng
- Qiongdan Mai (ORCID: https://orcid.org/0000-0002-7166-095X)
- Yuanping Tang
- Jie Wen (ORCID: https://orcid.org/0000-0001-7460-4219)
- Yasha Luo (ORCID: https://orcid.org/0000-0002-2690-0221)
- Yuan Chen (ORCID: https://orcid.org/0000-0002-1945-2512)
- Hongyu Li (ORCID: https://orcid.org/0000-0001-5521-8005)
- Yanting Qin
- Wenyu Deng
- Junfei Guo (ORCID: https://orcid.org/0000-0001-7903-8252)
- Weiming Lai
- Rongjia Mai
Institutions
- Chaozhou Central Hospital (CN)
- Guangdong Province Women and Children Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s12879-025-11577-z
- Citations
- 4
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 4.73
Funders
- Guangdong Medical Research Foundation