LncRNA B4GALT 1-AS1/miR-144-3p axis suppresses cytotoxicity of CD8+ T cells in lung adenocarcinoma by modulating PD-L1 expression
This study demonstrated that the B4GALT1-AS1/miR-144-3p axis suppressed the cytotoxicity of CD8<sup>+</sup> T cells in LUAD by modulating the expression of PD-L1, which will assist in innovating new immunotherapies.
Authors
- Lifei Huang (ORCID: https://orcid.org/0000-0002-2107-5808)
- Jiadong Wu
- Yahong Sun (ORCID: https://orcid.org/0009-0005-0119-0250)
- Zhihao Liu (ORCID: https://orcid.org/0000-0002-0643-442X)
- Yi Yang
Institutions
- First People's Hospital of Nanning (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1007/s12672-025-03295-4
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00