Inferring germline pharmacogenomics from tumor transcriptome
The leukemia transcriptome can be used to provide accurate genotyping calls for select germline pharmacogenes actionable in the treatment of pediatric ALL.
Authors
- Ching‐Hon Pui (ORCID: https://orcid.org/0000-0003-0303-5658)
- Kim E. Nichols (ORCID: https://orcid.org/0000-0002-5581-6555)
- Cyrine E. Haidar (ORCID: https://orcid.org/0000-0002-8998-2551)
- Gang Wu (ORCID: https://orcid.org/0000-0002-1678-5864)
- Jeffery M. Klco (ORCID: https://orcid.org/0000-0003-2961-6960)
- Wenjian Yang (ORCID: https://orcid.org/0000-0002-7305-5649)
- Nickhill Bhakta (ORCID: https://orcid.org/0000-0001-5282-7833)
- Sima Jeha (ORCID: https://orcid.org/0000-0003-2835-5869)
- Jun J. Yang (ORCID: https://orcid.org/0000-0002-0770-9659)
- Hiroto Inaba (ORCID: https://orcid.org/0000-0003-0605-7342)
- Ulrich Broeckel
Institutions
- St. Jude Children's Research Hospital (US)
Publication Details
- Journal
- Pharmacogenetics and Genomics
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1097/fpc.0000000000000576
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00