Diosmetin ameliorates inflammation and apoptosis in the pathomechanism of PCOS through the NRF2/AKT/PPARγ signalling pathway
The present study confirms that DIO has important therapeutic potential for treating polycystic ovary syndrome by inhibiting ovarian inflammation and oxidative stress through the modulation of AKT/PPARγ signalling.
Authors
- Mengting Chen (ORCID: https://orcid.org/0000-0001-6001-9270)
- Xiong Yuan
- Zhiquan Qin
- Yu Chen (ORCID: https://orcid.org/0000-0002-5473-8022)
- Yuan Liu (ORCID: https://orcid.org/0000-0003-4783-5905)
- Xiaohui Cao (ORCID: https://orcid.org/0009-0004-9565-5532)
- Jingwen Meng
- Yafang Jin
Institutions
- Nanjing Maternity and Child Health Care Hospital (CN)
- Jiangxi Maternal and Child Health Hospital (CN)
- Lishui Maternity and Child Health Care Hospital (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1186/s13048-025-01788-y
- Citations
- 3
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 3.88