Differential regulation of mesoscale chromosome conformations in osteoblasts and osteosarcoma
Our findings provide new insights into the coordinated complex regulatory mechanisms governing mesoscale chromosome organization in normal and transformed osteogenic tissues.
Authors
- Yu-Chieh Chung (ORCID: https://orcid.org/0000-0002-9430-8393)
- Sydney Willey (ORCID: https://orcid.org/0009-0005-4263-7848)
- Li‐Chun Tu (ORCID: https://orcid.org/0000-0002-7421-4007)
- Benjamin Z. Stanton (ORCID: https://orcid.org/0000-0002-2613-2955)
- Benjamin D. Sunkel (ORCID: https://orcid.org/0000-0003-1376-9567)
- Madhoolika Bisht
- Meng Wang (ORCID: https://orcid.org/0000-0002-3457-5908)
- Siou-Luan He (ORCID: https://orcid.org/0009-0007-2249-2228)
Institutions
- Nationwide Children's Hospital (US)
- University of Michigan (US)
- The Ohio State University (US)
Publication Details
- Journal
- Genome biology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1186/s13059-025-03785-2
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ohio State University
- Francis Crick Institute
- National Institutes of Health
- National Cancer Institute
- National Institute of General Medical Sciences