Establishment of an Advanced In Vitro Model for Pseudoexfoliation Syndrome and Glaucoma
This advanced in vitro model, which recapitulates the hallmark of PEX syndrome/glaucoma, may provide a useful, easy-to-handle platform for studying disease mechanisms, assessing the impact of genetic and external factors, and exploring effects of targeted therapies for PEX-associated fibrosis.
Authors
- Francesca Pasutto (ORCID: https://orcid.org/0000-0002-0026-5362)
- Matthias Zenkel (ORCID: https://orcid.org/0000-0003-0141-120X)
- Klaus Korn (ORCID: https://orcid.org/0000-0003-1891-2107)
- Anselm Jünemann
- Ursula Schlötzer-Schrehardt
- Robert Lämmer
- Friedrich E. Kruse
- Sai Pulasani
- Andreas Gieβl
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- FMP Technology (Germany) (DE)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1167/iovs.66.12.61
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft