Development of Vancomycin Population Pharmacokinetic Models for Pediatric Patients Using a Real-World Web Application Database
For Japanese pediatric patients aged 3 months or older, the developed popPK model is suitable for both empirical and Bayesian-guided vancomycin dosing. Two-point sampling improves the accuracy of clearance estimation and is recommended when feasible.
Authors
- Hideki Kawamura (ORCID: https://orcid.org/0000-0001-9073-972X)
- Kensuke Shoji (ORCID: https://orcid.org/0000-0002-7164-0262)
- Kazuaki Matsumoto (ORCID: https://orcid.org/0000-0002-5462-1684)
- Toshimi Kimura (ORCID: https://orcid.org/0000-0001-6990-425X)
- Kazutaka Oda (ORCID: https://orcid.org/0000-0003-0693-1896)
- Yoshio Takesue (ORCID: https://orcid.org/0000-0002-8635-6416)
- Aizawa Shigemi
Institutions
- Hyogo Medical University (JP)
- Keio University (JP)
- Juntendo University (JP)
- Kagoshima University Hospital (JP)
- Kumamoto University Hospital (JP)
- National Center For Child Health and Development (JP)
- Juntendo University Hospital (JP)
- Tokushima Municipal Hospital (JP)
Publication Details
- Journal
- Journal of the Pediatric Infectious Diseases Society
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1093/jpids/piaf087
- Citations
- 1
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 1.39