Attention-Enhanced CNNs and transformers for accurate monkeypox and skin disease detection

Monkeypox has arisen as a global health issue, requiring prompt and precise diagnosis for optimal management. Conventional diagnostic techniques, including PCR, are dependable yet frequently unattainable in resource-constrained environments. Deep learning demonstrates potential in automating disease detection from skin lesion images; nevertheless, current models are hindered by limits in feature extraction and misclassification challenges. This paper presents an attention-augmented deep learning architecture to enhance classification accuracy for monkeypox and other dermatological conditions. This work presents a model based on EfficientNetB7, augmented with coordinate attention to enhance feature extraction and classification accuracy. The Monkeypox Skin Lesion Dataset (MSLD v2.0) is utilised, incorporating pre-processing methods such as image normalisation, scaling, and data augmentation. Diverse edge detection techniques are examined to enhance feature representation. The model is subjected to five-fold cross-validation and is evaluated against Xception, Swin Transformer, ResNet-50, MobileNetV2, and baseline EfficientNet models, utilising accuracy, precision, recall, F1-score, and AUC as assessment measures. Our model attains an unparalleled accuracy of 99.99%, precision of 99.8%, recall of 99.9%, F1-score of 99.85%, and an AUC of 100%. In contrast to previous studies that indicated a maximum accuracy of 98.81%, our methodology markedly diminishes false negatives and improves generalisation. This research sets a novel standard for AI-based monkeypox detection, showcasing exceptional accuracy and resilience. The results endorse the incorporation of AI-driven diagnostic tools in clinical and telemedicine settings, with prospects for immediate implementation and extensive epidemiological monitoring.

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Publication Details

Journal
Scientific Reports
Published
2025-09-25
DOI
https://doi.org/10.1038/s41598-025-12216-y
Citations
6
Primary Topic
Poxvirus research and outbreaks
Type
article
Field-Weighted Citation Impact
6.22

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article

Attention-Enhanced CNNs and transformers for accurate monkeypox and skin disease detection

Magdi A. A. Mousa, Hossam M. Kasem, Roayat Ismail Abdelfatah, Abdelrahman T. Elgohr et al.
6 citations
Scientific Reports
Poxvirus research and outbreaks
6.22
article

Attention-Enhanced CNNs and transformers for accurate monkeypox and skin disease detection

Magdi A. A. Mousa, Hossam M. Kasem, Roayat Ismail Abdelfatah, Abdelrahman T. Elgohr, Ahmed Safwat, Mohamed S. Elhadidy
article en
6 citations

Abstract

Monkeypox has arisen as a global health issue, requiring prompt and precise diagnosis for optimal management. Conventional diagnostic techniques, including PCR, are dependable yet frequently unattainable in resource-constrained environments. Deep learning demonstrates potential in automating disease detection from skin lesion images; nevertheless, current models are hindered by limits in feature extraction and misclassification challenges. This paper presents an attention-augmented deep learning architecture to enhance classification accuracy for monkeypox and other dermatological conditions. This work presents a model based on EfficientNetB7, augmented with coordinate attention to enhance feature extraction and classification accuracy. The Monkeypox Skin Lesion Dataset (MSLD v2.0) is utilised, incorporating pre-processing methods such as image normalisation, scaling, and data augmentation. Diverse edge detection techniques are examined to enhance feature representation. The model is subjected to five-fold cross-validation and is evaluated against Xception, Swin Transformer, ResNet-50, MobileNetV2, and baseline EfficientNet models, utilising accuracy, precision, recall, F1-score, and AUC as assessment measures. Our model attains an unparalleled accuracy of 99.99%, precision of 99.8%, recall of 99.9%, F1-score of 99.85%, and an AUC of 100%. In contrast to previous studies that indicated a maximum accuracy of 98.81%, our methodology markedly diminishes false negatives and improves generalisation. This research sets a novel standard for AI-based monkeypox detection, showcasing exceptional accuracy and resilience. The results endorse the incorporation of AI-driven diagnostic tools in clinical and telemedicine settings, with prospects for immediate implementation and extensive epidemiological monitoring.

Scientific ReportsVol. 15(1)
Damietta University (EG), Prince Sattam Bin Abdulaziz University (SA), Tanta University (EG), Egypt-Japan University of Science and Technology (EG)
Prince Sattam bin Abdulaziz University, Egypt-Japan University of Science and Technology
Openalex Percentile: Top 3%
Poxvirus research and outbreaks
6.22
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