Oral Cephalexin Population Pharmacokinetics and Target Attainment Analysis in Infants 7-60 Days Old
Oral cephalexin can achieve necessary pharmacodynamic targets in infants 7-60 days old. These findings support the use of model-informed dosing strategies to guide safe and effective oral antibiotic use in early infancy, including for IV-to-oral transition.
Authors
- Marc H. Scheetz (ORCID: https://orcid.org/0000-0002-1091-6130)
- Sonya Tang Girdwood (ORCID: https://orcid.org/0000-0001-7737-8499)
- Andrew S. Haynes (ORCID: https://orcid.org/0000-0001-5486-0522)
- Peter L. Anderson (ORCID: https://orcid.org/0000-0002-1200-8494)
- Charles A. Peloquin (ORCID: https://orcid.org/0000-0001-9002-7052)
- Kevin Messacar (ORCID: https://orcid.org/0000-0001-5830-3491)
- Daniel González (ORCID: https://orcid.org/0000-0001-5522-5686)
- Douglas N. Fish (ORCID: https://orcid.org/0000-0002-1750-6230)
- Zixuan Wei (ORCID: https://orcid.org/0000-0001-7016-2775)
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Midwestern University (US)
- Duke University (US)
- American Association of Colleges of Pharmacy (US)
- University of Florida (US)
- Clinical Research Institute (US)
- Children's Hospital Colorado (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Montana (US)
- University of Cincinnati Medical Center (US)
- University of Colorado Denver (US)
- Florida College (US)
Publication Details
- Journal
- Journal of the Pediatric Infectious Diseases Society
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1093/jpids/piaf088
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00