Association between lipid profile components and health-related quality of life among hospitalized patients with cirrhosis
We disentangled the association between increased HDL-C levels and better EQ-5D-defined HRQoL in hospitalized cirrhotics. Furthermore, the dose-response relationship between HDL-C and EQ-5D utility index differed between males and females, suggesting sex-dimorphic mechanisms linking HDL-C to HRQoL. If validated in interventional studies, sex-specific HDL-C pathway modulation might inform future adjunctive approaches.
Authors
- Wentian Liu (ORCID: https://orcid.org/0000-0002-0944-9387)
- Chao Sun (ORCID: https://orcid.org/0000-0002-0380-7999)
- Gaoyue Guo (ORCID: https://orcid.org/0009-0005-1796-7159)
- Xuqian Zhang (ORCID: https://orcid.org/0000-0003-1388-993X)
- Binxin Cui (ORCID: https://orcid.org/0009-0003-9771-3073)
Institutions
- China Aerospace Science and Industry Corporation (China) (CN)
- Tianjin Medical University General Hospital (CN)
Publication Details
- Journal
- Postgraduate Medicine
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1080/00325481.2025.2567229
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00