Effects of transcranial direct current stimulation on neuro electrical activity in mice with migraine

These results establish that low-intensity tDCS ameliorates migraine pathophysiology through dual mechanisms: <i>θ</i>-band synchronization mediating behavioral normalization and <i>γ</i>-band desynchronization reducing neural noise. The <i>δ</i>/θ power reconfiguration implicates thalamocortical rhythm stabilization as a potential therapeutic target, advancing our mechanistic understanding of non-invasive neuromodulation in migraine management.