Bone marrow mesenchymal stem cell-derived exosomal microRNA-335 alleviates vascular calcification by targeting SP1
This study highlights that BMSC-derived exosomes regulate VC via the miR-335/SP1 axis, offering novel molecular targets for treating VC.
Authors
- Chuanzhen Chen (ORCID: https://orcid.org/0000-0001-6970-9446)
- Mei Huang (ORCID: https://orcid.org/0000-0001-9693-0701)
- Yaodong Li (ORCID: https://orcid.org/0000-0003-3742-1944)
- Jingbo Kong
- Cunfa Liu
- Liguo Liu (ORCID: https://orcid.org/0000-0002-6064-8701)
- Bing Dai
- Junjie Huang
Institutions
- Tianjin Hospital (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3389/fcvm.2025.1572045
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Tianjin Municipal Health Commission