Germline homologous recombination repair (gHRR) variants in bladder cancer: Preliminary evidence and clinical implications
Germline HRR variants are prevalent in BC patients and may influence disease aggressiveness and treatment decisions. These findings support broader implementation of germline testing in BC and warrant further validation in larger cohorts.
Authors
- Pier Paolo Avolio (ORCID: https://orcid.org/0000-0002-7497-265X)
- Rosanna Asselta (ORCID: https://orcid.org/0000-0001-5351-0619)
- Alessio Benetti (ORCID: https://orcid.org/0000-0002-4168-5259)
- Vittorio Fasulo
- Nicolò Maria Buffi
- Anita Capalbo (ORCID: https://orcid.org/0000-0002-8399-4463)
- Giovanni Lughezzani (ORCID: https://orcid.org/0000-0003-3939-4521)
- Massimo Lazzeri (ORCID: https://orcid.org/0000-0002-4411-3715)
- Paolo Casale (ORCID: https://orcid.org/0000-0002-7899-5736)
- Giulia Soldà (ORCID: https://orcid.org/0000-0003-0972-610X)
- Marco Paciotti (ORCID: https://orcid.org/0000-0002-8456-6495)
- Paolo Pietro Bianchi (ORCID: https://orcid.org/0000-0002-2690-3502)
- Alberto Saita (ORCID: https://orcid.org/0000-0003-0000-5517)
- Alessio Finocchiaro
- Pietro Cavalli
- Rodolfo Hurle
- F. Sormani
Institutions
- Humanitas University (IT)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- BJUI Compass
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1002/bco2.70077
- Primary Topic
- DNA Repair Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00