AURKA Enhances Antitumor Immunity by Activating CD4+ T Cell Proliferation in Colorectal Cancer

AURKA dually regulates tumor proliferation and immune engagement. Its spatial enrichment in T-cell niches supports its use as an immunotherapy biomarker.

Authors

Jiazi Yu (ORCID: https://orcid.org/0000-0002-8919-1178)
Zhongchen Liu (ORCID: https://orcid.org/0000-0002-3541-2211)
Wei Wang (ORCID: https://orcid.org/0000-0001-9705-5769)
Jianpei Zhao
Xiaoyu Dai (ORCID: https://orcid.org/0000-0003-3630-6039)
Yidong Xu

Institutions

Tongji University (CN)
Shenyang Anorectal Hospital (CN)
Ningbo No. 2 Hospital (CN)
Ningbo Medical Center Lihuili Hospital (CN)
Shanghai Tenth People's Hospital (CN)
Ningbo No.6 Hospital (CN)

Publication Details

Journal: Cancer Investigation
Published: 2025-09-25
DOI: https://doi.org/10.1080/07357907.2025.2559403
Primary Topic: Microtubule and mitosis dynamics
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

AURKA Enhances Antitumor Immunity by Activating CD4+ T Cell Proliferation in Colorectal Cancer

Jiazi Yu, Zhongchen Liu, Wei Wang, Jianpei Zhao et al.

Sep 25, 2025

Cancer Investigation

Microtubule and mitosis dynamics

article

AURKA Enhances Antitumor Immunity by Activating CD4+ T Cell Proliferation in Colorectal Cancer

Jiazi Yu, Zhongchen Liu, Wei Wang, Jianpei Zhao, Xiaoyu Dai, Yidong Xu

September 25, 2025article en

Abstract

AURKA dually regulates tumor proliferation and immune engagement. Its spatial enrichment in T-cell niches supports its use as an immunotherapy biomarker.

Cancer InvestigationVol. 43(9)

Tongji University (CN), Shenyang Anorectal Hospital (CN), Ningbo No. 2 Hospital (CN), Ningbo Medical Center Lihuili Hospital (CN), Shanghai Tenth People's Hospital (CN), Ningbo No.6 Hospital (CN)

Openalex Percentile: Top 72%

Microtubule and mitosis dynamics

DOI Source OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

AURKA Enhances Antitumor Immunity by Activating CD4+ T Cell Proliferation in Colorectal Cancer — Jiazi Yu, Zhongchen Liu, et al. · Cancer Investigation (2025) | TGRS Research Map | TGRS