Multi-omics analysis reveals ultraviolet response insights for immunotherapy and prognosis
We reveal for the first time that UVR is strongly associated with ICI resistance. The UVR.Sig feature offers the potential to identify patients who respond to immunotherapy and to tailor BRCA treatment strategies.
Authors
- Jiafei Ying
- Danhua Zhang (ORCID: https://orcid.org/0000-0001-6801-7536)
- Yifan Huang (ORCID: https://orcid.org/0000-0002-6883-9158)
- Zixuan Liu (ORCID: https://orcid.org/0000-0002-4728-4149)
- Mei Dai
- ChenLu Wu (ORCID: https://orcid.org/0009-0000-1342-3641)
Institutions
- Central South University (CN)
- Hunan Provincial Center for Disease Control and Prevention (CN)
- Shaoxing City Women and Children Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-26
- DOI
- https://doi.org/10.3389/fimmu.2025.1598070
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00