Genome-wide association study of chlamydia reinfection in African American women

This GWAS study in AA women identified multiple novel genes associated with chlamydia reinfection, including <i>CHIT1, CHI3L1, ADORA1, ALK, TDRP, FBXO25, LINC01592, SULF1</i>, and <i>SOCS6</i>, which are involved in the immune response. <i>CHIT1, ADORA1, CHI3L1, TDRP, FBOXO25</i>, <i>SULF1</i>, and <i>SOCS6</i> were identified using CI/eQTL mapping.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-09-25
DOI
https://doi.org/10.3389/fimmu.2025.1594317
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
0.00

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article

Genome-wide association study of chlamydia reinfection in African American women

Mary Appah, Vinodh Srinivasasainagendra, Amit Patki, William M. Geisler et al.
Frontiers in Immunology
Reproductive tract infections research
article

Genome-wide association study of chlamydia reinfection in African American women

Mary Appah, Vinodh Srinivasasainagendra, Amit Patki, William M. Geisler, Kanupriya Gupta, Archish Sadeesh, Sandeep C Vejandla
article en

Abstract

This GWAS study in AA women identified multiple novel genes associated with chlamydia reinfection, including <i>CHIT1, CHI3L1, ADORA1, ALK, TDRP, FBXO25, LINC01592, SULF1</i>, and <i>SOCS6</i>, which are involved in the immune response. <i>CHIT1, ADORA1, CHI3L1, TDRP, FBOXO25</i>, <i>SULF1</i>, and <i>SOCS6</i> were identified using CI/eQTL mapping.

Frontiers in ImmunologyVol. 16
University of Alabama at Birmingham (US), McMaster University (CA)
Georgia Clinical and Translational Science Alliance, National Institutes of Health, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences
Openalex Percentile: Top 76%
Reproductive tract infections research
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