The abscopal effect in metastatic lung cancer: a retrospective analysis of combined radiotherapy and immunotherapy
While the AbE remains an intriguing phenomenon, its occurrence was rare and not significantly associated with OS. Strategic RT site selection and optimized treatment sequencing were more strongly linked to improved survival outcomes, highlighting the need for refined radioimmunotherapy strategies.
Authors
- Sonia Ziegler (ORCID: https://orcid.org/0000-0001-8655-3172)
- Rami A. El Shafie (ORCID: https://orcid.org/0000-0002-1355-7882)
- Sandra Donath
- Manuel Guhlich (ORCID: https://orcid.org/0000-0002-2599-6196)
- David Alexander Ziegler (ORCID: https://orcid.org/0000-0002-1469-8767)
- Markus Schirmer (ORCID: https://orcid.org/0000-0003-1375-4496)
- Laura Anna Fischer
- Achim Rittmeyer (ORCID: https://orcid.org/0000-0002-5280-6052)
- Stefan Andreas (ORCID: https://orcid.org/0000-0003-3918-6909)
- Martin Leu (ORCID: https://orcid.org/0000-0002-3883-6837)
- Leif H. Dröge (ORCID: https://orcid.org/0000-0002-5378-4246)
- Stefan Rieken (ORCID: https://orcid.org/0009-0000-7018-2856)
- Alexander Freiherr von Hammerstein-Equord (ORCID: https://orcid.org/0000-0002-0026-284X)
- Friederike Braulke
- Markus Ambold
- Jona Bensberg
- Lisa Antonia von Diest
- Benedikt Kieslich
Institutions
- Universitätsmedizin Göttingen (DE)
- German Center for Lung Research (DE)
- Medizinische Universität Lausitz - Carl Thiem (DE)
- University of Göttingen (DE)
Publication Details
- Journal
- Clinical & Experimental Metastasis
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1007/s10585-025-10375-w
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00