Femoral arteriovenous concentration differences reveal metabolomic shifts in peripheral artery disease (PAD): A case–control study
Using the femoral AV concentration differences of metabolites, we identified significant local metabolomic shifts in the PAD group. Most of these changes were not revealed using traditional upper-limb venous blood sampling. Further study of AV differences could improve the understanding of the pathophysiology of PAD.
Authors
- Jaak Kals (ORCID: https://orcid.org/0000-0002-8745-718X)
- Kaido Paapstel (ORCID: https://orcid.org/0000-0003-2968-6512)
- Kalle Kilk (ORCID: https://orcid.org/0000-0003-4551-9466)
- Mihkel Zilmer (ORCID: https://orcid.org/0000-0002-1337-594X)
- Jaan Eha (ORCID: https://orcid.org/0000-0001-5049-4852)
- Tuljo Ööbik (ORCID: https://orcid.org/0009-0001-6071-6954)
Institutions
- Tartu University Hospital (EE)
- University of Tartu (EE)
Publication Details
- Journal
- Vascular Medicine
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1177/1358863x251370352
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00