Dependence and clinical fragility in hematopoietic stem cell transplant and CAR-T therapy: a retrospective study
Our findings may contribute to improving personalized assessment strategies in the field of cell therapy, including both CAR-T therapy and stem cell transplantation. They highlight the increased risk and complexity of care, particularly in patients receiving CAR-T therapy, while emphasizing the need for tailored management approaches across different cell therapy modalities.
Authors
- Domenico Pascucci (ORCID: https://orcid.org/0000-0002-5804-2284)
- Chiara Visintini (ORCID: https://orcid.org/0000-0003-1174-741X)
- Marco Cioce (ORCID: https://orcid.org/0000-0003-0345-5468)
- Nicola Nicolotti (ORCID: https://orcid.org/0000-0002-3096-6397)
- Matteo Raponi (ORCID: https://orcid.org/0000-0001-8688-9960)
- Sarah Liptrott (ORCID: https://orcid.org/0000-0001-9499-6002)
- Simona Calza (ORCID: https://orcid.org/0000-0003-3235-5175)
- Carmen Nuzzo
- Patrizia Cornacchione (ORCID: https://orcid.org/0000-0002-5573-6352)
- Stefano Botti (ORCID: https://orcid.org/0000-0002-0678-0242)
- Angela Iula (ORCID: https://orcid.org/0000-0003-3508-3283)
- Giuseppe Vetrugno (ORCID: https://orcid.org/0000-0003-0181-2855)
- Simona Sica (ORCID: https://orcid.org/0000-0003-2426-3465)
- Patrizia Laurenti (ORCID: https://orcid.org/0000-0002-8532-0593)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Istituto Giannina Gaslini (IT)
- Agostino Gemelli University Polyclinic (IT)
- Azienda Sanitaria Unità Locale di Reggio Emilia (IT)
- Ente Ospedaliero Cantonale (CH)
- Advanced Radiation Therapy (United States) (US)
- Ospedale Regionale di Bellinzona e Valli (CH)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Supportive Care in Cancer
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1007/s00520-025-09925-5
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università Cattolica del Sacro Cuore