Transcranial ultrasound tomography for brain imaging: Ex vivo results and potential for stroke imaging

This work shows that UST imaging of the brain is feasible through a skull-mimicking phantom for a variety of targets. In silico, in vitro and ex vivo targets could all be visualized in sound speed images with a skull phantom present despite the presence of cycle skipping artifacts. Additionally, an intact human brain sample was imaged to demonstrate our current ability to visualize anatomical features, and therefore guide future development of this work.

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Publication Details

Journal
Medical Physics
Published
2025-09-24
DOI
https://doi.org/10.1002/mp.18090
Primary Topic
Photoacoustic and Ultrasonic Imaging
Type
article
Field-Weighted Citation Impact
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article

Transcranial ultrasound tomography for brain imaging: Ex vivo results and potential for stroke imaging

Edward Vates, Matthew T. Bender, Derrek Schartz, Trevor Mitcham et al.
Medical Physics
Photoacoustic and Ultrasonic Imaging
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Transcranial ultrasound tomography for brain imaging: Ex vivo results and potential for stroke imaging

Edward Vates, Matthew T. Bender, Derrek Schartz, Trevor Mitcham, Melanie Singh, Redi Rahmani, Rehman Ali, N. Duric, Sarah McConnell
article en

Abstract

This work shows that UST imaging of the brain is feasible through a skull-mimicking phantom for a variety of targets. In silico, in vitro and ex vivo targets could all be visualized in sound speed images with a skull phantom present despite the presence of cycle skipping artifacts. Additionally, an intact human brain sample was imaged to demonstrate our current ability to visualize anatomical features, and therefore guide future development of this work.

Medical PhysicsVol. 52(10)
University of Louisville (US), University of Rochester (US)
Openalex Percentile: Top 75%
Photoacoustic and Ultrasonic Imaging
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