Case Report: Treatment of facial pyoderma gangrenosum with Upadacitinib
Pyoderma gangrenosum (PG) is a recurrent, painful, necrotizing ulcerative neutrophilic dermatosis. Facial PG (FPG) is a rare subtype of PG that is often misdiagnosed. A 20-year-old male with FPG showed improvement after treatment with a combination of prednisone and upadacitinib. Early diagnosis is crucial to avoid misdiagnosis.
Authors
- Li‐Rui Zhan (ORCID: https://orcid.org/0000-0002-6331-0407)
- Gai Ge
- Jinbo Chen (ORCID: https://orcid.org/0000-0002-9665-8506)
- Fei Su (ORCID: https://orcid.org/0009-0003-4121-0944)
- Jing Dong (ORCID: https://orcid.org/0000-0002-9353-2246)
- Meng Huang (ORCID: https://orcid.org/0000-0003-1666-2853)
Institutions
- Wuhan No.1 Hospital (CN)
- Institute of Infection and Immunity (CA)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fmed.2025.1665013
- Primary Topic
- Autoimmune and Inflammatory Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00