Evaluating the prognostic value of TP53 mutations in acute leukemia: a comprehensive retrospective study from a tertiary care hospital
This study shows that TP53 mutations significantly worsen the prognosis of acute leukemia. Routine TP53 mutation screening should be integrated into clinical practice to refine risk stratification and guide treatment, while prospective studies are needed to validate these findings and explore targeted therapies.
Authors
- Weizhou Li (ORCID: https://orcid.org/0000-0002-3673-4976)
- Fang Liu (ORCID: https://orcid.org/0000-0003-3028-5927)
- Ting Hu (ORCID: https://orcid.org/0000-0002-0759-2817)
- Li-Ping Peng
Institutions
- Jiangxi Pingxiang People's Hospital (CN)
Publication Details
- Journal
- Hematology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1080/16078454.2025.2552428
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00