Thymidine kinase 1 related to Prolif-like T cells promoted GBM through regulation of cell cycle and EMT signals: a comprehensive research based on multi-omics analysis and experimental validation
TK1, as a Prolif-like T cell-associated marker, promotes GBM progression and can serve as a potential therapeutic target for GBM.
Authors
- Xiaoting Chang (ORCID: https://orcid.org/0000-0003-3224-3624)
- Wentao Deng (ORCID: https://orcid.org/0000-0001-6501-1737)
- Wei Shang (ORCID: https://orcid.org/0000-0002-2218-0810)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Jiangjin Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fimmu.2025.1655980
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00