Personalized prediction of pathological complete response in breast cancer neoadjuvant therapy: a nomogram combining quantitative MRI biomarkers and molecular subtypes
Breast MRI accuracy was reduced in ER-negative tumors, those lacking DCIS, and lesions exhibiting coexistent mass and NME. A clinicopathological-MRI integrated nomogram demonstrated robust predictive performance for pCR after NAT completion, potentially aiding in surgical strategy planning.
Authors
- Hanyan Zhu
- Qian Xiao-min (ORCID: https://orcid.org/0000-0002-8308-8508)
- Xiaoxing Bian
- Jin Zhang (ORCID: https://orcid.org/0009-0003-1166-2958)
- Chunyan Li (ORCID: https://orcid.org/0000-0001-9499-3047)
- Peng Zhou (ORCID: https://orcid.org/0000-0002-5036-545X)
- Jie Meng (ORCID: https://orcid.org/0000-0002-6367-0568)
- Zhendong Shi
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fonc.2025.1669700
- Citations
- 1
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Tianjin Medical University
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences