Association between the aspartate aminotransferase-to-alanine aminotransferase ratio and the reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study
Our study revealed that the AST/ALT ratio is independently related to reversion to normoglycemia in pre-diabetic Chinese people. The relationship between the AST/ALT ratio and reversion to normoglycemia from IFG is nonlinear. There is a significant positive relationship between the AST/ALT ratio and reversion to normoglycemia when the AST/ALT ratio is >1.13.
Authors
- Haofei Hu (ORCID: https://orcid.org/0000-0001-6061-6796)
- Rong Rong (ORCID: https://orcid.org/0000-0003-2423-4082)
- Zhe Deng (ORCID: https://orcid.org/0000-0002-9776-7261)
- Kebao Zhang (ORCID: https://orcid.org/0000-0002-3317-634X)
- Liting Xu
- Lifen Xu
- Lidan Chen (ORCID: https://orcid.org/0000-0003-4974-7642)
- Shuting Zeng (ORCID: https://orcid.org/0009-0000-9323-1331)
Institutions
- Sun Yat-sen University (CN)
- Shenzhen Second People's Hospital (CN)
- Anshan Hospital (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fendo.2025.1546202
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00