Body mass, linear growth, and body composition before and after the introduction of elexacaftor/tezacaftor/ivacaftor among children and adults with cystic fibrosis
Children with CF continued to increase their BMZ 2 years post-ETI initiation, while HAZ remined stable. The rate of change in BMI returned to pre-ETI trends among adults with CF. Adult BMI gains were primarily driven by an increase of fat mass.
Authors
- Inger Hee Mabuza Mathiesen (ORCID: https://orcid.org/0000-0003-2398-3575)
- Bibi Uhre Nielsen (ORCID: https://orcid.org/0000-0003-0622-5262)
- Søren Jensen‐Fangel
- Espen Jimenez‐Solem (ORCID: https://orcid.org/0000-0002-3777-147X)
- Majbritt Jeppesen
- Marianne Nielsine Skov (ORCID: https://orcid.org/0000-0002-2619-0864)
- Daniel Faurholt‐Jepsen (ORCID: https://orcid.org/0000-0001-8561-0155)
- Karlen S Bader-Larsen (ORCID: https://orcid.org/0000-0003-3233-8703)
- Peter Oturai (ORCID: https://orcid.org/0000-0002-9828-9185)
- Hans Kristian Pedersen (ORCID: https://orcid.org/0009-0005-7959-1548)
- Camilla Bjørn Jensen (ORCID: https://orcid.org/0000-0002-8224-4601)
- Janne Petersen (ORCID: https://orcid.org/0000-0001-7323-2548)
- Christian Leo‐Hansen (ORCID: https://orcid.org/0000-0003-2004-6404)
- Hanne Vebert Olesen (ORCID: https://orcid.org/0000-0003-4000-210X)
- Thomas Bryrup (ORCID: https://orcid.org/0000-0001-8533-6766)
- Christine Højte
- Bente Langdahl (ORCID: https://orcid.org/0000-0002-8712-7199)
- Tavs Qvist (ORCID: https://orcid.org/0000-0002-1725-5312)
- Tacjana Pressler (ORCID: https://orcid.org/0000-0002-6434-4975)
- Mette Frahm Olsen (ORCID: https://orcid.org/0000-0002-5742-6403)
- Joanna Wang (ORCID: https://orcid.org/0000-0003-1723-1342)
- Hanne Olsen
- Esben Herborg Henriksen (ORCID: https://orcid.org/0000-0002-1247-8779)
- E. Henriksen
- Terese Katzentein
Institutions
- University of Copenhagen (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Danish Pain Research Center (DK)
Publication Details
- Journal
- Clinical Nutrition
- Published
- 2025-09-25
- DOI
- https://doi.org/10.1016/j.clnu.2025.09.008
- Citations
- 1
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Vertex Pharmaceuticals