Boosting the engraftment of subcutaneously transplanted pancreatic islets by nanofat

These findings demonstrate that nanofat markedly boosts the vascularisation and endocrine function of islet grafts. Hence, its co-transplantation with pancreatic islets represents a simple, clinically feasible approach to make the subcutaneous space available for future islet transplantation.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2025-09-24
DOI
https://doi.org/10.1111/dom.70127
Primary Topic
Pancreatic function and diabetes
Type
article
Field-Weighted Citation Impact
0.00

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article

Boosting the engraftment of subcutaneously transplanted pancreatic islets by nanofat

Emmanuel Ampofo, Andrea Weinzierl, Michael D. Menger, Matthias W. Laschke et al.
Diabetes Obesity and Metabolism
Pancreatic function and diabetes
article

Boosting the engraftment of subcutaneously transplanted pancreatic islets by nanofat

Emmanuel Ampofo, Andrea Weinzierl, Michael D. Menger, Matthias W. Laschke, Sandra Rother, Bruce Morgan, Leticia Prates‐Roma, Selina Wrublewsky, Charlotte Berhorst, Caroline Bickelmann, Cedric Wilden, Lea Stefanie Meßmer
article en

Abstract

These findings demonstrate that nanofat markedly boosts the vascularisation and endocrine function of islet grafts. Hence, its co-transplantation with pancreatic islets represents a simple, clinically feasible approach to make the subcutaneous space available for future islet transplantation.

Diabetes Obesity and MetabolismVol. 27(12)
University Hospital of Zurich (CH), Saarland University (DE)
Universität des Saarlandes, Servier
Openalex Percentile: Top 58%
Pancreatic function and diabetes
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