Case Report: Food-based enteral formula in the nutritional management of children with hyperinsulinism: single center retrospective case series

Our retrospective case series suggests that FBF is well tolerated in children with hyperinsulinism and may mitigate gut motility issues associated with hyperinsulinism, especially in relation to gastro-esophageal reflux and constipation symptoms. Furthermore, FBF may help reduce the dependency on glucose polymers and reduce the likelihood of a hyperglycemic episode. A larger sample size and longer follow-up study are necessary to substantiate the potential beneficial impact of FBF's on glucose control in children with hyperinsulinism.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-09-25
DOI
https://doi.org/10.3389/fendo.2025.1574093
Primary Topic
Hyperglycemia and glycemic control in critically ill and hospitalized patients
Type
article
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article

Case Report: Food-based enteral formula in the nutritional management of children with hyperinsulinism: single center retrospective case series

Graeme O’Connor, Lauren Cheng, Annaruby Cunjamalay
Frontiers in Endocrinology
Hyperglycemia and glycemic control in critically ill and hospitalized patients
article

Case Report: Food-based enteral formula in the nutritional management of children with hyperinsulinism: single center retrospective case series

Graeme O’Connor, Lauren Cheng, Annaruby Cunjamalay
article en

Abstract

Our retrospective case series suggests that FBF is well tolerated in children with hyperinsulinism and may mitigate gut motility issues associated with hyperinsulinism, especially in relation to gastro-esophageal reflux and constipation symptoms. Furthermore, FBF may help reduce the dependency on glucose polymers and reduce the likelihood of a hyperglycemic episode. A larger sample size and longer follow-up study are necessary to substantiate the potential beneficial impact of FBF's on glucose control in children with hyperinsulinism.

Frontiers in EndocrinologyVol. 16
Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
Openalex Percentile: Top 64%
Hyperglycemia and glycemic control in critically ill and hospitalized patients
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