Distinct clinical and laboratory markers associated with disease duration and viral clearance in Foshan’s 2025 chikungunya outbreak

Elevated liver enzymes and reduced neutrophil counts were associated with longer symptom duration, while older age and prolonged joint pain, rash, and initial symptoms predicted delayed viral clearance. These findings may assist clinicians in identifying patients at risk of prolonged illness and inform targeted management strategies during CHIKV outbreaks in China and similar settings. Our study represents one of the first systematic analyses of clinical and laboratory markers associated with disease course and viral clearance in CHIKV-infected patients in China.