Prognostic impact of miR-17-5p and miR-20a-5p in NSCLC diverge in subgroups according to lymph node status
Overall, our results suggest that the prognostic role of miR-17-5p and miR-20a-5p in early-stage NSCLC is context-dependent. Consequently, further studies are needed to elucidate the role of these miRs during NSCLC carcinogenesis. Clinical implementation should not be initiated until their role in different disease settings is sufficiently understood.
Authors
- Tom Dønnem
- Dagny Førde
- Sigve Andersen (ORCID: https://orcid.org/0000-0002-2402-570X)
- Erna‐Elise Paulsen (ORCID: https://orcid.org/0000-0002-6907-1224)
- Mehrdad Rakaee (ORCID: https://orcid.org/0000-0002-9080-0153)
- Ana Paola G. Lombardi
- Thomas K. Kilvær (ORCID: https://orcid.org/0000-0003-1669-0117)
- Lill‐Tove Busund (ORCID: https://orcid.org/0000-0001-8235-6163)
- Mona Irene Pedersen
- Irene D’arsiè
Institutions
- Oslo University Hospital (NO)
- University Hospital of North Norway (NO)
- University of Trento (IT)
- UiT The Arctic University of Norway (NO)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-25
- DOI
- https://doi.org/10.3389/fonc.2025.1606933
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitetet i Tromsø
- Kreftforeningen
- Helse Nord RHF